Loss of Consciousness in a 50-yr-old Man

Essential Differential Diagnosis

Shortly after initial examination, the patient becomes extremely lethargic. He responds to deep pain by withdrawing, and he is able to protect his airway.

He is noted to have the following: heart rate 30 beats/min, BP 74/52 mm Hg, respirations 10/min, and pulse oximetry 94% on room air. His pupils remain equal and reactive.

At this time, which of the following differential diagnoses cannot be excluded based on history and physical examination in this patient? (You may select more than one option.)